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9 月 . 09, 2024 14:51 Back to list

Professional Veterinary Knowledge of Carbasalate Calcium

Professional Veterinary Knowledge of Carbasalate Calcium

Carbasalate calcium is a chelate of calcium acetylsalicylate and urea. This kind of chelation is not so solid, and often makes salicylic acid exceed the standard and its effect is not so ideal or even more obvious side effects. This is one of the drug defects that can only be solved by technology through the development of the formulation and the production of the product, so as to ensure or improve the quality of the drug.

 

Carbasalate calcium is sensitive to water, and the lower the moisture content of the preparation, the more stable the product is during long-term storage. If the moisture content of the product exceeds 2%, the product will be decomposed and decomposed over time to produce salicylic acid under the condition of water as a medium in the process of logistics and preservation. Especially in summer, the ambient temperature is relatively high, and the decomposition of Carbasalate calcium will be faster!

 

The metabolic characteristics and pharmacological effects of Carbasalate calcium are the same as those of aspirin. It has antipyretic, analgesic, anti-inflammatory and inhibits platelet aggregation to prevent thrombosis caused by various causes. Oral absorption is rapid, rapid onset, high bioavailability (higher than aspirin). Carbasalate calcium is metabolized by the liver and excreted by the kidneys. Its antipyretic and analgesic effect is stronger, the adverse reactions are small, and it has certain irritation to the gastrointestinal mucosa.

Carbasalate Calcium Powder

Under normal circumstances, Carbasalate calcium is a white crystalline powder with a slightly bitter taste and is highly soluble in water. Carbasalate Calcium is a new type of antipyretic analgesic and anti-inflammatory drug that can be used for symptomatic treatment of porcine febrile diseases, pain and various infections.

 

The main mechanism of action of Carbasalate calcium in livestock and poultry: Carbasalate calcium, which is orally administered into livestock and poultry, is first hydrolyzed to aspirin. Aspirin can then be rapidly absorbed, metabolized by the liver, and hydrolyzed to salicylic acid in the body. Finally, the purpose of antipyretic, analgesic and anti-inflammatory is achieved.

 

The main difference between Carbasalate calcium and other antipyretic and analgesic drugs is that in the anti-inflammatory effect, Carbasalate calcium has anti-inflammatory effects, but not for acetaminophen and aspirin.

 

In terms of solubility, both Carbasalate calcium and analgin are soluble in water, while aspirin is insoluble in water and acetaminophen is slightly soluble in water.

 

In terms of safety, Carbasalate calcium has few side effects, while aspirin easily causes gastrointestinal ulcers and hemorrhage; analgesic side effects are large, causing immunosuppression; acetaminophen side effects are relatively small.

 


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