Neomycin Sulfate Soluble Powder

Neomycin sulfate

This product is a kind of white to light yellow powder.

Pharmacodynamics Neomycin is an antibacterial drug derived from hydrogen glycoside rice. Its antibacterial spectrum is similar to that of kanamycin. It has strong antibacterial effect on most gram-negative bacteria, such as Escherichia coli, Proteus, Salmonella and Pasteurella multocida, and is also sensitive to Staphylococcus aureus. Pseudomonas aeruginosa, gram-positive bacteria (except Staphylococcus aureus), Rickettsia, anaerobes and fungi are resistant to this product.
Pharmacokinetics Neomycin is rarely absorbed after oral administration and local application. After oral administration, only 3% of the total amount of neomycin is excreted from urine, and most of it is excreted from feces without change. Intestinal mucosa inflammation or ulcers can increase absorption. The drug is absorbed quickly after injection, and its internal process is similar to that of kanamycin.

(1) Combined with macrolide antibiotics, it can treat mastitis caused by gram-positive bacteria.
(2) Oral administration can affect the absorption of digitalis, vitamin A or vitamin B12.
(3) It has synergistic effect with penicillin or cephalosporin.
(4) The antibacterial effect of this product is enhanced in alkaline environment, and it is compatible with alkaline drugs (such as sodium bicarbonate, aminophylline And so on) can enhance the antibacterial effect, but the toxicity is also correspondingly enhanced. Antibacterial when pH exceeds 8.4 On the contrary, the effect is weakened.
(5) Cations such as Ca2+, Mg2+, Na+, NH and K+can inhibit the antibacterial activity of the product.
(6) Combined with cephalosporin, dextran, powerful diuretics (such as furosemide), erythromycin, etc., it can Enhance the ototoxicity of this product.
(7) Skeletal muscle relaxants (such as succinylcholine chloride) or drugs with this effect can strengthen the Neuromuscular block effect.

Aminoglycoside antibiotics. It is mainly used to dry treat gastrointestinal infection caused by sensitive gram-negative bacteria.

Calculated by this product. Mixed drinking: 1.54~2.31g poultry per 1L of water. It can be used continuously for 3~5 days.

Neomycin is the most toxic in aminoglycosides, but few toxic reactions occur when it is administered orally or locally.

Chickens that lay eggs for human consumption shall not be used during the laying period.

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